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A Brief Introduction to Cannabinoids

While medical cannabis or marijuana is nothing new, it is a plant that was illegal for years that carried an extremely negative stigmatism held by many. Interestingly enough, this plant that has been deemed dangerous for so long is now saving people’s lives.

While most people by now know that marijuana has huge medical benefits, many are still unaware of exactly how it works as a medicine. Welcome to the world of cannabinoids, the chemical compounds of cannabis that are responsible for its medicinal make-up.

What are Cannabinoids?

You’re probably most familiar with THC (tetrahydrocannabinol) and perhaps have heard a thing or two about CBD (cannabidiol). These are the two major cannabinoids found in marijuana that are responsible for the amazing medical benefits the plant contains. How exactly do these two cannabinoids work as medicine, though?

It’s all about a harmonious synergy that takes place within your body and mind when you medicate with marijuana. Our bodies naturally produce compounds called endocannabinoids which help us maintain health and stability. When there’s a problem with these endocannabinoid compounds, we experience internal instability, sickness, and disease. The cannabinoids found in marijuana (namely THC and CBD) do an excellent job of replicating the compounds our bodies produce and help to bring back our health to a natural balance.

When we ingest cannabis, the cannabinoids it contains bind to different receptor sites within our body. In our brains they bind to receptors CB-1 and in our bodies to receptors CB-2. Different cannabinoids have shown to attach themselves to different receptor sites. THC reacts with the CB-1 receptors in our brains, while CBD binds with the CB-2 receptors found in our body.

If you’re familiar with medical marijuana, you’re well aware that there are certain strains that are higher in THC while some contain a higher amount of CBD. When you know what cannabinoid helps with what medical condition, you’re able to target the right receptor with the right cannabinoid and easily find the relief you seek.

There are over 85 cannabinoids found in cannabis, and it’s not just THC and CBD that show promise as medicine. THCa, CBG, CBN, THCv, and CBDa are all other cannabinoids that have shown to help with various medical conditions.

Which Cannabinoid is Best for Which Condition?

THC and CBD are the most widely known and both are used by medical marijuana dispensaries pretty much everywhere. Knowing what cannabinoid treats what is an awesome way to become familiar with what would be best to treat your own unique medical needs and take control of how you medicate. Before your next trip to the dispensary don’t forget that you can find tons of strains that will deliver different dosages of each. Knowing whether a THC or CBD strain is best for your condition is something you definitely want to know.


As the most well-known cannabinoids, THC is the one responsible for the psychoactive state of mind experienced when consuming cannabis. It’s amazing for a host of various health conditions including:


For those who don’t like to feel “stoned” but still are still interested in the medical benefits of cannabis, there is CBD. CBD actually counteracts the psychoactive properties of THC, making it an excellent choice for those who don’t wish to “get high.” CBD is beneficial for the following conditions:

While CBD and THC treat many of the same conditions, CBD-rich strains provide an alternative for those who don’t wish to experience the psychoactive effects that THC induces. It’s also been extremely popular amongst parents whose children suffer from seizures at its shown to completely eliminate them without the need for any additional medication.

If you’re going to medicate yourself, be sure to educate yourself. Knowing what makes medical marijuana actually medicine will help you to better understand why this increasingly popular plant works so well…to make you well.

If you are interested in trying CBD products, shop with Buy My Weed Online where you will find various CBD tinctures, sprays, patches, gels, jellies, oils, and even pet treats and salve. We also have a variety of THC products to choose from including our many strains of heady cannabis and THC isolates, tinctures, and sprays.


Works Cited:

  1. An introduction to the endocannabinoid system
  2. Cannabinoid Receptors and the Endocannabinoid System: Signaling and Function in the Central Nervous System
  3. Molecular Targets of the Phytocannabinoids-A Complex Picture
  4. What is THC?
  5. How cannabis affects appetite: Brain changes
  6. A Systematic Review of the Effectiveness of Medical Cannabis for Psychiatric, Movement and Neurodegenerative Disorders
  7. Effects of Marijuana on Mental Health: Bipolar Disorder
  8. “I Use Weed for My ADHD”: A Qualitative Analysis of Online Forum Discussions on Cannabis Use and ADHD
  9. Cannabinoids inhibit cellular respiration of human cancer cells
  10. Cannabinoids in the Management of Musculoskeletal Pain: A Critical Review of the Evidence 
  11. A pilot study of the effects of cannabis on appetite hormones in HIV-infected adult men.
  12. Emerging Role of (Endo)Cannabinoids in Migraine
  13. Cannabis Use and Blood Pressure Levels: United States National Health and Nutrition Examination Survey, 2005–2012
  14. Epilepsy and Cannabis: A Literature Review
  15. Asthma: How should cannabis or THC be taken to treat asthma?
  16. Marijuana as Medicine? The Science Beyond the Controversy.
  17. Cannabidiol in Anxiety and Sleep: A Large Case Series
  18. Menstrual Cramps and Marijuana Research Overview
  19. The Anti-Inflammatory Properties of Terpenoids from Cannabis
  20. Relieving Phantom Pain and Opioid Dependency with Medicinal Marijuana
  21. Cannabis for chronic pain: case series and implications for clinicians.
  22. Decreased depression in marijuana users
  23. Marijuana Use by Patients with Multiple Sclerosis
  24. Role of cannabis in digestive disorders

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